Purinergic Regulation of Respiratory Diseases

The first integrated analysis of all aspects of purinergic signaling in the respiratory system, this book covers everything from the basics of purinergic pharmacology and metabolism to the latest research into its effect on respiratory diseases such as asthma.

Furthermore, the critical analysis of past clinical protocols should facilitate the identification of potent therapeutic targets, and provide a better understanding of the data acquired in current clinical trials.

Dedication. Preface.- Chapter 1. Nucleotide Release by Airway Epithelia.- Chapter 2. Mechanisms Regulating Airway Nucleotides.- Chapter 3. Computational Model for the Regulation of Extracellular ATP and Adenosine in Airway Epithelia.- Chapter 4. Regulation of Airway Nucleotides in Chronic Lung Diseases.- Chapter 5. Nucleotide-Mediated Airway Clearance.- Chapter 6. Purinergic Signaling in Wound Healing and Airway Remodeling.- Chapter 7. Purinergic Regulation of Airway Inflammation.- Chapter 8. Animal Models of Airway Diseases.- Chapter 9. Therapeutic Applications. Index