Providing coverage of pharmacogenomics, this work leads to the understanding of the key genetic differences between individuals and permits the individual tailoring of pharmacological treatments. It also contributes to the discovery of new targets for drug development.

This is the very first comprehensive coverage of pharmacogenomics a new discipline that will revolutionize health care. "Pharmacogenomics" leads to the understanding of the key genetic differences between individuals and will permit the individual tailoring of pharmacological treatments. Improved therapeutics can reach new levels by being able to differentiate between individuals according to their susceptibility to disease processes or adverse effects of medication. "Pharmacogenomics" also contributes to the discovery of new targets for drug development. Outstanding experts in the field present an overview of the latest work in this young and promising approach and provide an insight into the recent findings for all relevant disease classes. It is indispensable for a wide audience of experts working in the various areas that contribute to this field such as pharmacology, genetics, molecular biology, pharmaceutics, medicinal chemistry and clinical medicine.

Introduction to Pharmacogenomics: Promises, Opportunities, and Limitations
The Human Genome
Turning SNPs into Useful Markers of Drug Response
Association Studies in Pharmacogenomics
Genomics Applications that Facilitate the Understanding of Drug Action and Toxicity
The Role of Pharmacogenomics in Drug Discovery and Therapeutics
Pharmacogenomics and Drug Design
The Pharmacogenomics of Human P glycoprotein
Pharmacogenomics of Drug Transporters
Pharmacogenomics of Asthma Treatment
Endothelial Cells are Targets for Hydroxy Urea: Relevance to the Current Therapeutic Strategy in Sickle Cell Disease
Pharmacogenomics and Complex Cardiovascular Disease
Clinical Studies in Candidate Genes
Pharmacogenomics of Lipid lowering Agents
Pharmacogenomics of Chemotherapeutic Agents in Cancer Treatment
Pharmacogenomics of the Blood Brain Barrier
Pharmacogenomics and the Treatment of Neurological Disease
Pharmacogenomics of Neurodegenerative Diseases: Examples and Perspectives
Psychiatric Pharmacogenomics: Prediction of Treatment Outcomes in Schizophrenia
Pharmacogenomics of Major Depression and Antidepressant Treatment
Pharmacogenomics of Bipolar Disorder
Pharmacogenomics of Alcoholism
Pharmacogenomics of Tobacco Addiction
Pharmacogenomics of Opioid Systems
Ethnicity and Pharmacogenomics
Pharmacogenomics: Ensuring Equity Regarding Drugs Based on Genetic Difference
Translation of Vascular Proteomics into Individualized Therapeutics
Glossary of Key Terms in Molecu lar Genetics of Pharmacogeno mics
Index