Presents a review on Alzheimer's Disease as well as a look at several transcription factors. This volume provides clinical features of stroke and the current stasis of stroke therapy. It also talks about Alzheimer's Disease - pathology, pathological proteins, etiology, pathogenesis, neurotransmitter alterations, and treatment strategies.

Volume 42 presents an in-depth review on Alzheimer's Disease as well as a look at several transcription factors. Among its key features, it: provides clinical features of stroke and the current stasis of stroke therapy; talks about Alzheimer's Disease - pathology, pathological proteins, etiology, pathogenesis, neurotransmitter alterations, and treatment strategies; presents an examination of the regulation of AP-1 and related transcription factors and their role in brain injury and drug abuse-related behavior; talks about emerging roles of the transcription factor NF (B Recent advances about the nature of alterations in ion channel structure or function which may be responsible for epileptogenesis; presents an integrated model accounting for the multiple mechanisms involved in the posttranslational regulation of glutamate ionotroic receptors; and covers Genetic mutation and the Glycine Receptor.

M.A. Smith, Alzheimer Disease. W.D. Dietrich, Neurobiology of Stroke. M.P. Mattson, Free Radicals, Calcium, and Synaptic Plasticity-Cell Death Continuum: Emerging Roles of the Transcription Factor NFk B. K. Pennypacker, AP-1 Transcription Factors: Short- and Long-Term Modulators of Gene Expression in the Brain. I. Mody, Ion Channels in Epilepsy. X. Bi, S. Standley, and M. Baudry, Posttranslational Regulation of Ionotropic Glutamate Receptors and Synaptic Plasticity. B. Vafa and P.R. Schofield, Heritable Mutations in the Glycine, GABAA, and Nicotinic Acetycholine Receptors Provide New Insights into the Ligand-Gated Ion Channel Receptor Superfamily. Chapter References. Index. Contents of Recent Volumes.