Combined Modality Therapy of Central Nervous System Tumors

The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumours of the central nervous system in 2000. Major developments in new technologies in the treatment of primary brain tumours as well as metastatic disease are covered in depth.

The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000, with about 200,000 individuals presenting with brain metastases. The advances in the treatment of solid tumors have contributed significantly to the major increase in metastatic cancers to the brain. Of the primary malignant tumors of the brain, more than 50 per cent are high-grade gliomas; the incidence has been increasing among older patients over the past decade. Major developments in new technologies in the treatment of primary brain tumors as well as metastatic disease are covered in depth. Even though management is difficult, advances are being made. This book is a concerted effort to present data regarding basic science research efforts alongside their translation into clinical practice using combined, integrated multimodal programs of treatment. Progress has been made, but innovatice approaches need to be pursued.

Management of Low-grade Gliomas: A Surgical Perspective - L.T. Khoo and M.L.J. Apuzzo
Radiotherapy in the Management of Low-grade Gliomas - R.D. Kortmann, B. Jeremic, and M. Bamberg
Surgical Therapy and Problems in the Treatment of Private Malignant Gliomas -M. Salcman
Radiation Therapy Principles for High-grade Gliomas - C.T. Miyamoto
The Role of Stereotactic Radiosurgery in the Management of Primary Brain Tumors -D. Huang, J. Chen, C. Yu, and Z. Petrovich
Frameless Stereotactic Radiosurgery - S.D. Chang, M.J. Murphy, D.P. Martin, and J.R. Adler, Jr.
Treatment of Brain Metastasis - Z. Petrovich, C. Yu, and M.L.J. Apuzzo
Management of Skull Base Tumors - J.D. Day and R.A. Freidman
Treatment of CNS Lymphomas - S.C. Formenti and A. Bettini
Chemotherapy in Adult CNS Tumors - S. ODay and B. Dykes
Immunotherapy for Primary Brain Tumors - J.E. Lahaniatis and L.W. Brady
Prospects for Gene Therapy for Brain Tumors - V.C.-K. Tse and G. Harsh
Radiation Therapy in the Management of Pediatric Brain Tumors - R.S. Lavey
Surgical Management of Pediatric Patients with CNS Tumors - M.D. Krieger, J.G. McComb, and M. Levy
Chemotherapy in Pediatric Patients - D.J. Hyder
Surgery for Primary and Metastatic Tumors of the Spine - A.T. Parsa, B.D. Birch, M.G. Kaiser, and P.C. McCormick
Radiotherapy of Tumors of the Spine - Z. Petrovich, M. Liker, and G. Jozsef
Management of Rare Central Nervous System Tumors - G. Hsu and R. Sawaya
Toxicity of Therapy and Quality of Life of Patients Treated for CNS Tumors - S.C. Formenti and Z. Petrovich
Complexity of Nursing Care in Patients Undergoing Treatment for CNS Tumors - E.M. Thomson
Subject Index
List of Contributors.