Clinical Research in Oral Health

* * Exclusively focused on research within the oral sciences * Provides guidance in all aspects of clinical research, from essential principles to logistics * Clarifies the framework of regulatory issues for researchers and study staff * Presents emerging concepts in translational research.

Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.

1 Clinical and Translational Research: Implications in the Promotion of Oral Health William V. Giannobile
2 Ethics in Oral Health Research Elizabeth Ripley, Francis L. Macrina
3 Responsibilities of Institutions and Individuals in Clinical Research in the Oral Health Sciences Gary C. Armitage
4 Regulatory Process for the Evaluation of Dental Drugs, Devices and Biologics Darnell Kaigler, Kay Fuller, William V. Giannobile
5 Clinical and Translational Research Grantsmanship: Funding Opportunities and Obtaining Research Support Bruce L. Pihlstrom, Michael L. Barnett
6 Data Management in Oral Health Research Bruce A. Dye, Jules T. Mitchel
7 Hypothesis Testing and Avoiding False-Positive Conclusions Philippe P. Hujoel
8 Outcomes in Oral Health Research Amid I. Ismail
9 Examiner Training: Standardization and Calibration in Periodontal Studies Niklaus P. Lang, Mary P. Cullinan, Douglas W. Holborow, Lisa J.A. Heitz-Mayfield
10 Observational Studies in Oral Health Research Hal Morgenstern, Woosung Sohn
11 Initial Clinical Trials Allow Assessment of Safety, Dosing and Preliminary Efficacy Prior to Large Randomized Controlled Pivotal Studies
Jules T. Mitchel, Glen Park, Mark Citron, Russ Pagano, Leslie Wisner-Lynch, Samuel E. Lynch
12 Phase III Pivotal Clinical Trials: Clinical Decision-making Norman S. Braveman, Bryan Michalowicz
13 Post-Marketing Surveillance Eugenio D. Beltran-Aguilar, Michael C. Manz
14 Dental Practice-Based Research Networks Donald J. DeNucci and the CONDOR Dental Practice-based Research Networks
15 The Technology Transfer Process for Life Science Innovations in Academic Institutions Robert J. Genco
16 Adoption of New Technologies for Clinical Practice Maxwell H. Anderson
17 Publication of Research Findings James Bader
18 The Evidence-base for Oral Health Helen Worthington, Ian Needleman, Anne-Marie Glenny