Cavernous Malformations of the Brain and Spinal Cord

Provides information on surgical indications and treatments for cavernous malformations, including cavernous angioma, cavernoma, and cavernous hemangioma. This book is intended for neurosurgeons and neurologists, particularly those treating patients with seizures and hemorrhagic stroke.

This book presents a comprehensive overview of the basic science and current clinical knowledge on cavernous malformations of the brain and spinal cord. Cavernous Malformations of the Brain and Spinal Cord begins by covering general aspects of the disease, including the natural history, molecular biology, pathological processes, genetic basis, neuroradiology, and classification of cavernous malformations. Separate chapters then address the various types of cavernous malformations, thoroughly describing the clinical presentation and management approaches for each clinical situation. Incisive review of recent literature sheds light on topics of incidence, location, and outcomes.

I. General Aspects
1) Epidemiology and Natural History
2) Molecular Biology
3) Pathology
4) Genetic Transmission &
Familial Forms
5) Cavernous Malfrmations as a Dynamic Lesson: de novo formation, radiological changes, and radiatiom induced forms
6) Capillary teleangectasia, cavernous malformations, and developmental venous anomalies: different expresions of the same disease process?
7) Classification and neuroradiology of cavernous malformations
II. Clinical Presentation, Indications for Surgery, Surgical Techniques and Outcome
1) Supratentorial lobar cavernous malformations
2) Deep-seated supratentorial cavernous malformations: basal ganglia and thalamus
3) Brainstem and cerebellar cavernous malformations
4) Spinal Cord Cavernous Malformations
5) Cavernous Malformations in Atypical Locations (Cranial Nerves, Ventricles, Extraaxial)
6) Cavernous malformations