Covering advances in immunology, this volume gives an organizational and structural overview of the human IgH, reviews IFN-g's biological function, provides comparisons of structural and kinetic properties of PGHS-1 and 2, and considers tumour antigens and their role in immunogenicity.

F. Matsuda and T. Honjo, Organization of the Human Immunoglobulin Heavy-Chain Locus. J. Chen, Analysis of Gene Function in Lymphocytes by RAG-2-Deficient Blastocyst Complementation. A. Billiau, Interferon-gamma: Biology and Role in Pathogenesis. K.S. Hathcock and R.J. Hodes, Role of the CD28-B7 Costimulatory Pathways in T Cell-Dependent B Cell Responses. W.L. Smith and D.L. DeWitt, Prostaglandin Endoperoxide H Synthases-1 and -2. R.A. Hendersonand O.J. Finn, Human Tumor Antigens Are Ready to Fly. N.W. Lukacs and P.A. Ward, Inflammatory Mediators, Cytokines, and Adhesion Molecules in Pulmonary Inflammation and Injury. Chapter References. Subject Index. Contents of Recent Volumes.