A survey of current, mainly clinical research on the treatment of primary breast cancer is summarized in these papers stemming from the 4th International Conference on Adjuvant Therapy of Primary Breast Cancer held in St Gallen, Switzerland in 1992.

An up-to-date survey of current, mainly clinical research on the treatment of primary breast cancer is summarized in these papers stemming from the 4th Intemational Conference on Adjuvant Therapy of Primary Breast Cancer held in St. Gallen, Switzerland, in 1992. The papers cover relevant topics from biological mechanisms on cell kUl and overcoming drug resistance to new aspects of breast conserving surgery and adjuvant endocrine as well as cytotoxic therapies. They update the results of most of the important intenational trials on adjuvant therapy of breast cancer. The closing summary reporting the common opinions of an intenational consensus on risk-adapted adjuvant therapy of breast cancer, which sets the stage for optimal treatment of breast cancer patients both clinically and psycho-socially, is particularly timely.