Introduces the theory and application of 3D QSAR analyses to both the novice and the experienced user and gives a comprehensive overview of the scope and limitations of these methods. This book deals with the theoretical background of 3D QSAR and discussion of CoMFA applications.

Its content, starting at a very elementary level and proceeding to the latest methodological results, the strengths and limitations of 3D QSAR approaches, makes the book also appropriate as a text for teaching and for graduate student courses.